Photodynamic Therapy (PDT):
Sustainable Treatment of Precancerous Skin Lesions
Photodynamic Therapy (PDT) is a modern, non-invasive procedure for treating precursors of non-melanoma skin cancer, such as actinic keratoses, as well as certain types of white skin cancer, particularly superficial basal cell carcinomas (BCC).
In our dermatological practice in Berlin-Zehlendorf, we perform PDT exclusively as a laser-assisted procedure. Our goal is to achieve highly effective results while ensuring excellent aesthetic outcomes.
What is Laser-Assisted Photodynamic Therapy (PDT)?
During laser-assisted PDT in Berlin-Zehlendorf, the skin is specifically prepared before the actual treatment. Using a laser, microscopically fine micro-channels are created in the upper layers of the skin. These allow the active ingredient to penetrate deeper and more evenly into the diseased skin cells.
Subsequently, a specialized cream containing a photosensitizer is applied, which selectively accumulates in the affected cells. After an incubation period of approximately 3–4 hours, the cells are activated by a specific light source.
The treated areas typically heal without scarring within a few weeks. Often, one to two sessions are required to achieve optimal results.
Which Skin Irregularities Can Be Treated with PDT?
The efficacy of Photodynamic Therapy is scientifically well-documented for:
| Actinic Keratoses: | Early forms/precursors of non-melanoma skin cancer caused by chronic UV exposure. Typical areas include the face, scalp, décolleté, and the back of the hands. |
| Superficial Basal Cell Carcinomas (BCC): | The most common form of non-melanoma skin cancer. Basal cell carcinomas grow in a locally destructive manner but do not metastasize; they should be treated early. |
Long-lasting Treatment of Precancerous Lesions
- Modern, non-surgical treatment for non-melanoma skin cancer
- Laser-assisted drug penetration via micro-channels
- Excellent cosmetic results
- Detection of clinically invisible skin irregularities (field cancerization)
- Typically scar-free healing
- Prevention of invasive forms of skin cancer
Frequently Asked Questions
What are the alternatives to PDT?
For isolated, clearly defined lesions, a CO2 laser treatment in our dermatology practice in Berlin-Zehlendorf may be a viable alternative. In this case, individual actinic keratoses are precisely removed layer by layer.
For larger areas or multiple skin irregularities, laser-assisted PDT is usually the more effective therapy, as it also treats microscopic lesions that are not yet visible.
Additionally, topical cream therapies may be appropriate in some cases.
What are the side effects of PDT?
During conventional PDT, a burning or stinging sensation may occur during light exposure. In the days following both conventional and daylight PDT, redness, oozing, or crusting may occur. In approximately 30% of cases, a second treatment may be necessary.
What should I keep in mind after PDT?
- Avoid direct sun exposure for 24 hours.
- Strict sun protection for 14 days.
- Use sunblock with a very high SPF, especially on the face.
- Avoid mechanical irritation of the treated skin.
- Apply nourishing creams/serums to accelerate wound healing.
